dominoSignal - Cell Communication Analysis for Single Cell RNA Sequencing
dominoSignal is a package developed to analyze cell signaling through ligand-receptor-transcription factor networks in scRNAseq data. It takes as input information transcriptomic data, requiring counts, z-scored counts, and cluster labels, as well as information on transcription factor activity (such as from SCENIC) and a database of ligand and receptor pairings (such as from CellPhoneDB). This package creates an object storing ligand-receptor-transcription factor linkages by cluster and provides several methods for exploring, summarizing, and visualizing the analysis.
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systemsbiologysinglecelltranscriptomicsnetworksequencing
7.04 score 8 stars 33 scripts 318 downloadsscatterHatch - Creates hatched patterns for scatterplots
The objective of this package is to efficiently create scatterplots where groups can be distinguished by color and texture. Visualizations in computational biology tend to have many groups making it difficult to distinguish between groups solely on color. Thus, this package is useful for increasing the accessibility of scatterplot visualizations to those with visual impairments such as color blindness.
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visualizationsinglecellcellbiologysoftwarespatial
5.02 score 7 stars 15 scripts 348 downloads